The centers housed within the College of Technology take advantage of the research expertise of faculty members by focusing their efforts on specific topics.

From aviation research to technology development, and from professional studies to product lifecycle management, the centers help address current industry issues and provide solutions.

The Advanced Aviation Analytics Institute for Research (A³IR- CORE), a University-level Center of Research Excellence that resides in the Department of Aviation Technology, is focused on the dual mission of solving industry problems and providing educational experiences for students by actively involving both graduate and undergraduate student researchers working closely with faculty mentors in a highly-collaborative multidisciplinary environment.

(AirTIES) aims to facilitate academic and industry researchers in developing aviation alternative fuels solutions for practical use in aviation.

The mission of the Biotechnology Innovation and Regulatory Science Center is to develop global programs to ensure sustainable access to medicines for Africa and developing nations, and to advance discovery in manufacturing technology, quality of medicines, and rare disease research. We accomplish this mission through innovative knowledge-based programs in STEM areas with an emphasis on interdisciplinary collaboration.

(ProSTAR) offers many of the College of Technology's master's degrees in a format that works well for professionals who want to work while they earn their degree

(CTD) develops innovative technologies focused on product, process, system and manufacturing efficiency.

The mission of PEGASAS is to enhance general aviation safety, accessibility, and sustainability by partnering the FAA with a national network of world-class researchers, educators and industry leaders.

(ICBR) engages industry on projects that involve testing and evaluation of technologies and protocols, develop global standards for the use of biometric technologies, develop innovative performance metrics, and apply their Human Biometric Sensor Interaction (HBSI) model to a variety of technologies.

(PLM) is an interdisciplinary research center that draws on expertise from all areas of the Purdue community to provide knowledge and tools.

Materials processing technology is a multidisciplinary field. Advanced materials processing technology plays an increasing important role in the global economy and in daily life.

The Research Center for Open Digital Innovation strives to engage in a revolution of innovation, researching the best way digital technologies can shape the process of open innovation. Open innovation combines an organization’s own research with additional information from external sources to solve problems and develop new products or services.